During decades of activity in this field, the syntheses of several hundreds of organic compounds labelled with 14C or 3H radioisotopes have been developed for pharmacological or metabolism (ADME) studies of drugs, agrochemicals (pesticides), bioactive compounds, etc. – the main application of radioisotope tracing.
A lot of C-14 labelled substances have also been produced as the intermediate for other laboratories, some of them in large scale as well.
Custom synthesis service of labelled compounds includes either the large-scale or the small-scale radiochemical total synthesis of the material with the required specific activity. A detailed quality certificate stating the purity, the specific activity and the total activity is issued.
The facility provides a tritium labelling to customers whose NRC license, facilities or safety concerns limit the amount of tritium that may be handled in their laboratories. The labelling includes the incorporation of tritium into target precursor, according to the customer’s demand, the removal of catalyst and labile tritium from the crude product and the determination of total activity.
Radiochemical repurification service for C-14, H-3 labelled compounds is also available.
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